Endogenous Receptor Agonists: Resolving Inflammation
نویسندگان
چکیده
منابع مشابه
Total synthesis of the endogenous inflammation resolving lipid resolvin D2 using a common lynchpin
The total synthesis of the endogenous inflammation resolving eicosanoid resolvin D2 (1) is described. The key steps involved a Wittig reaction between aldehyde 5 and the ylide derived from phosphonium salt 6 to give enyne 17 and condensation of the same ylide with aldehyde 7 to afford enyne 11. Desilylation of 11 followed by hydrozirconation and iodination gave the vinyl iodide 4 and Sonogashir...
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ژورنال
عنوان ژورنال: The Scientific World JOURNAL
سال: 2007
ISSN: 1537-744X
DOI: 10.1100/tsw.2007.188